刘骥，理学博士、讲师

　　联系邮箱：ji.liu@qau.edu.cn

　　个人履历：

　　2008-09至2012-06，南华大学，生物技术，学士

　　2012-09至2019-01，中国海洋大学，生态学，硕博连读

　　2016-01至2017-11，英国University of East Anglia，生态学，联合培养博士

　　2019-07至今，青岛农业大学，海洋科学与工程学院，讲师

　　研究方向：

　　海洋微生物生态学、水产养殖环境微生物学

　　主要业绩：

　　主持山东省自然科学基金面上项目和青年项目各1项；参与国家重点研发计划重点专项1项，国家自然科学基金重大研究计划重点支持项目1项、面上项目3项、青年基金1项。在国际微生物顶刊Nature Microbiology、国际Top期刊Nature Communications和中科院一区Top期刊Microbiome和Journal of Hazardous Materials及《水产科学》等中外期刊共发表学术论文25篇，第一作者论文6篇（含共一）。以第一发明人获国家发明专利1项。参编《海洋微生物学》（第2版，科学出版社）。现任Frontiers in Marine Science、Frontiers in Immunology等期刊审稿专家。

　　代表性科研成果：

　　Curson A R J, Liu J, Martínez A B, Green R T, Chan Y, Carrión O, Williams B T, Zhang S H, Yang G P, Page P C B, Zhang X*, Todd J D*. Dimethylsulfoniopropionate biosynthesis in marine bacteria and identification of the key gene in this process. Nature Microbiology, 2017, 2: 17009.

　　Liu J#, Chen Y#, Sun B, Xu D, Wang J, Sun Z*, Liu P, Jing F, Song Y, Xia B*. Toxicological effects of micro/nanoplastics and benzo[a]pyrene on cellular and molecular responses of Apostichopus japonicus (Selenka, 1867) during intestinal regeneration. Journal of Hazardous Materials, 2025, 491, 138003.

　　Liu J, Xu D, Chen Y, Zhao C, Liu L*, Gu Y, Ren Y, Xia B*. Adverse effects of dietary virgin (nano)microplastics on growth performance, immune response, and resistance to ammonia stress and pathogen challenge in juvenile sea cucumber Apostichopus japonicus (Selenka). Journal of Hazardous Materials, 2022, 423(Part A): 127038.

　　Liu J#, Chen Y#, Song Y#, Xu D, Gu Y, Wang J, Song W, Sun B, Jiang Z, Xia B*. Evidence of size-dependent toxicity of polystyrene nano- and microplastics in sea cucumber Apostichopus japonicus (Selenka, 1867) during the intestinal regeneration. Environmental Pollution, 2024: 124394.

　　Liu J#, Zhang Y#, Liu JL, Zhong H, Williams B T, Zheng Y, Curson A R J, Sun C, Sun H, Song D, Mackenzie B W, Martínez A B, Todd J D*, Zhang X*. Bacterial dimethylsulfoniopropionate biosynthesis in the East China Sea. Microorganisms, 2021, 9(3): 657.

　　Liu J#, Wang Y#, Liu Y, Zhang X*. Ahrensia marina sp. nov., a dimethylsulfoniopropionate-cleaving bacterium isolated from seawater, and emended descriptions of the genus Ahrensia and Ahrensia kielensis. IJSEM, 2016, 66: 874–880.

　　Liu JL#, Liu J#, Zhang S, Liang J, Lin H, Song D, Yang G, Todd J D*, Zhang X*. Novel insights into bacterial dimethylsulfoniopropionate catabolism in the East China Sea. Frontiers in Microbiology, 2018, 9: 3206.

　　Zhang X*, Liu J, Liu JL, Yang G, Xue C, Curson A R J, Todd J D. Biogenic production of DMSP and its degradation to DMS—their roles in the global sulfur cycle. Science China Life Sciences, 2019, 62(10): 1296–1319.

　　Sun H, Liu J, Tan S, Zheng Y, Wang X, Liang J, Todd J D*, Zhang X*. Spatiotemporal distribution of bacterial dimethylsulfoniopropionate producing and catabolic genes in the Changjiang Estuary. Environmental Microbiology, 2021, 23(11): 7073–7092.

　　Xu D, Liu J, Gu Y, Chen Y, Zhao C, Sun G, Ren Y, Li C, Xia B*. Biosynthesis and isotopic routing of dietary protein by sea cucumber Apostichopus japonicus (Selenka): Evidence from compound-specific carbon stable isotope analysis. Journal of Agricultural and Food Chemistry, 2021, 69(49): 14802–14809.

　　Song D, Zhang Y, Liu J, Zhong H, Zheng Y, Zhou S, Yu M, Todd J D*, Zhang X*. Metagenomic insights into the cycling of dimethylsulfoniopropionate and related molecules in the eastern China marginal seas. Frontiers in Microbiology, 2020, 11: 157.

　　Gu Y, Xu D, Liu J, Chen Y, Wang J, Song Y, Sun B, Xia B*. Bioaccumulation of functionalized polystyrene nanoplastics in sea cucumber Apostichopus japonicus (Selenka, 1867) and their toxic effects on oxidative stress, energy metabolism and mitochondrial pathway. Environmental Pollution, 2023, 319: 121015.

　　Xia B, Song W, Liu J, Song Y, Xin Q, Xu P, Xu D*. Explore the gene regulation mechanism under high temperature and hypoxia stress in the sea cucumber Apostichopus japonicus by high-throughput RNA-seq technology. Aquaculture Reports, 2024, 36: 102151.

　　Wang J, Curson A R J, Zhou S, Carrión O, Liu J, Vieira A R, Walsham K S, Monaco S, Li C, Dong Q, Wang Y, Rivera P P L, Wang X, Zhang M, Hanwell L, Wallace M, Zhu X, Leão P N, Lea-Smith D J, Zhang Y, Zhang X*, Todd J D*. Alternative dimethylsulfoniopropionate biosynthesis enzymes in diverse and abundant microorganisms. Nature Microbiology, 2024, 9: 1979–1992.

　　Zheng Y, Wang J, Zhou S, Zhang Y, Liu J, Xue C, Williams B T, Zhao X, Zhao L, Zhu X, Sun C, Zhang H, Xiao T, Yang G, Todd J D*, Zhang X*. Bacteria are important dimethylsulfoniopropionate producers in marine aphotic and high-pressure environments. Nature Communications, 2020, 11: 4658.

　　Liu JL, Xue C, Wang J, Crombie A T, Carrión O, Johnston A W B, Murrell J C, Liu J, Zheng Y, Zhang X*, Todd J D*. Oceanospirillales containing the DMSP lyase DddD are key utilisers of carbon from DMSP in coastal seawater. Microbiome, 2022, 10: 110.

　　Williams B T, Cowles K, Martínez A B, Curson A R J, Zheng Y, Liu J, Newton-Payne S, Hind A J, Li C, Rivera P P L, Carrión O, Liu J, Spurgin L G, Brearley C A, Mackenzie B W, Pinchbeck B J, Peng M, Pratscher J, Zhang X, Zhang Y, Murrell J C, Todd J D*. Bacteria are important dimethylsulfoniopropionate producers in coastal sediments. Nature Microbiology, 2019, 4(11): 1815–1825.

　　刘骥, 陈艳茹, 侯竹美, 徐冬雪, 谷元雪, 宋文琦, 宋宜泽, 夏斌*. 仿刺参腐皮综合征病原灿烂弧菌RPA-Cas13a检测方法的建立. 水产科学, 2023, 42(4): 632–639.

　　张晓华*, 刘骥, 柳敬丽, 郑艳芬. DMSP的生物合成与裂解及其在硫循环中的作用. 中国科学基金, 2018, 3(5): 471–478.

　　刘骥, 夏斌, 侯竹美, 陈艳茹, 徐冬雪. 一种水产病原灿烂弧菌的检测方法: 中国, ZL202211207240.X, 2023-12-29.

　　(#，共同第一作者；*，通讯作者)